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Siccanin, 5 MG

Price$ 1,357.50
  • SKU: S-2767-5MG
  • Pack Size: 5 MG
Quantity
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NSC 135048; (-)-Siccanin

22733-60-4

342.5

C22H30O3

DMF, DMSO, Ethanol, Methanol

-20°C


Siccanin is an unusual fused phenolic pentacycle first isolated from Helminthosporium siccans and reported in 1962 as a potent antifungal agent. Siccanin inhibits succinate dehydrogenase in the terminal electron transport system. More recent studies note the proximity of the siccanin binding site to the quinone-binding site of the enzyme. Species-selective inhibition by siccanin is unique among succinate dehydrogenase inhibitors and offers a lead for new chemotherapeutics.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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