(3R,6S)-3-hydroxy-3-[(3-hydroxyphenyl)methyl]-1,4-dimethyl-6-[(4-nitro-1H-indol-3-yl)methyl]-2,5-piperazinedione
122380-18-1
438.4
C22H22N4O6
DMF, DMSO
-20°C
Description
Thaxtomin A is a member of the broader thaxtomin family of phytotoxins. Thaxtomins occur naturally in certain Streptomyces bacteria associated with crop diseases. These toxins are capable of inducing hypertrophy and necrosis in plant cells. As a result, thaxtomins are effective as herbicides. In the specific case of thaxtomin A, the mechanism of action responsible for these effects is believed to involve action on multiple target structures within the cell, including both the cell wall and the plasma membrane. Studies have also shown that exposure to thaxtomin A can cause the buildup of fibrous material in cellular cytoplasm. Although other thaxtomins exhibit similar effects, thaxtomin A shows higher levels of physiological activity than other members of the group. Demonstrated to be produced by bacterial nitrix oxide synthases (NOS).
Applications
• Diketopiperazine antibiotic
• Phytotoxin
• Herbicide
• Natural cellulose synthesis inhibitor
• Plant cell necrosis inducer
• Induces common scab disease of potato
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
