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Obeticholic Acid, 10 MG

Price$ 58.24
  • SKU: O-2600-10MG
  • Pack Size: 10 MG




May be dissolved in DMSO (50 mg/mL) and ethanol (30 mg/mL)



Obeticholic acid is a novel cholic acid analog which acts as a potent and selective FXR agonist (EC50= 99 nM). Displays anticholeretic activity in a rat model of cholestasis1 . Promotes adipocyte differentiation and regulates adipose cell function2 . Normalizes insulin sensitivity in a rabbit model of metabolic syndrome3 . A potentially new therapeutic agent for management of non-alcoholic fatty liver disease4 and NASH5 . Displays therapeutic benefit in patients with primary biliary cirrhosis6 . Active in vivo.



• Protective Effects of 6-Ethyl Chenodeoxycholic Acid, a Farnesoid X Receptor Ligand, in Estrogen-Induced Cholestasis

• The Farnesoid X Receptor Promotes Adipocyte Differentiation and Regulates Adipose Cell Function in Vivo

• FXR activation normalizes insulin sensitivity in visceral preadipocytes of a rabbit model of MetS

• FXR Agonists as Therapeutic Agents for Non-alcoholic Fatty Liver Disease

• Non-Alcoholic Steatohepatitis: From Pathophysiology to Novel Therapies

• Efficacy of Obeticholic Acid in Patients With Primary Biliary Cirrhosis and Inadequate Response to Ursodeoxycholic Acid


Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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