6-ECDCA; INT 747
459789-99-2
420.6
C26H44O4
DMSO, Ethanol, Methanol
-20°C
Obeticholic acid is a novel cholic acid analog which acts as a potent and selective FXR agonist (EC50= 99 nM). Displays anticholeretic activity in a rat model of cholestasis. Promotes adipocyte differentiation and regulates adipose cell function. Normalizes insulin sensitivity in a rabbit model of metabolic syndrome. A potentially new therapeutic agent for management of non-alcoholic fatty liver disease and NASH . Displays therapeutic benefit in patients with primary biliary cirrhosis. Active in vivo.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
