Procaspase-activating Compound 1
315183-21-2
392.5
C23H28N4O2
DMF, DMSO, Ethanol
-20°C
Procaspase-activating compound 1 (PAC-1) directly activates procaspase-3 to caspase-3, a transformation that allows induction of apoptosis even in cells that have defective apoptotic machinery. In cancer cells, PAC-1 had an ICvalue of 3 nM for induction of cell death, whereas in cells from adjacent normal tissue had ICvalues of 3.2-8.5 M.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
