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Zotarolimus, 5 MG

Price$ 141.25
  • SKU: Z-2597-5MG
  • Pack Size: 5 MG
Quantity
-
+

A-179578; ABT-578

221877-54-9

966.2

C52H79N5O12

DMF, DMSO, Ethanol

-20°C


Zotarolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by preparation of the 42-triflate ester, followed by displacement with tetrazole and purification of the two isomeric products. This structural change affords a less bioavailable product, a preferred profile for some applications. Like all tacrolimus analogues, zotarolimus binds to a receptor protein (FKBP12). The complex then binds to mTOR preventing it from interacting with target proteins. Zotarolimus is extensively cited in the literature with over 200 citations.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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