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Leflunomide, 500 MG

Price$ 507.00
  • SKU: L-2372-500MG
  • Pack Size: 500 MG
Quantity
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+

HW 486; SU 101; 5-methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide

75706-12-6

270.2

C12H9F3N2O2

DMF, DMSO, Ethanol

-20°C


Cell-permeable. An immunosuppressive agent. Inhibits T and B cell responses in vivo. Inhibitor of tyrosine phosphorylation (tyrosine kinase inhibitor), of dihydroorotate dehydrogenase, an enzyme for de novo pyrimidine synthesis, of TNFdependent NF-B activation, and of COX-2. The physiological activity of leflunomide is attributed mainly to its metabolite A77 1726.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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