284028-89-3
312.3
C14H11F3N2OS
DMF, DMSO
-20°C
XAV939 is a Tankyrase (TNKS) inhibitor (IC= 110 nM for TNKS1 and 4 nM for TNKS2). Antagonizes wnt signaling via stimulation ofcatenin degradation and stabilization of axin. Inhibits proliferation of the-catenin-dependent colon carcinoma cell line DLD-1.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.