Soluble in DMSO. Dilute with destilled water or buffer, pH 7.0-7.5
Bongkrekic acid is an inhibitory ligand of the mitochondrial adenine nucleotide translocase (ANT) the inner membrane channel of the mitochondrial permeability transition pore (MPTP). It is a natural toxin when it contaminates food products.
It is a polyunsaturated long-chain fatty acid derivative that acts as a potent inhibitor of ANT. This acid blocks NMDA receptor and prevents PARP cleavage and DEVDase(Caspase-2 like) activity so that it inhibits apoptosis of cerebrocortical neurons.
Not for human therapeutic use or for medicinal purposes. For research applications only.
Research or further manufacturing use only, not for food or drug use.