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Bongkrekic Acid, 100 UG

Price$ 243.00
  • SKU: B-1053-100UG
  • Pack Size: 100 UG
Quantity
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Frequently Bought Together

Total price: $ 638.00

This item: Bongkrekic Acid, 100 UG $ 243.00

G-418 Sulfate, 25 G $ 395.00

11076-19-0

537.7 Da

C28H38O7•3NH3

Soluble in DMSO. Dilute with destilled water or buffer, pH 7.0-7.5

-20°C


Description

Bongkrekic acid is an inhibitory ligand of the mitochondrial adenine nucleotide translocase (ANT) the inner membrane channel of the mitochondrial permeability transition pore (MPTP). It is a natural toxin when it contaminates food products.

It is a polyunsaturated long-chain fatty acid derivative that acts as a potent inhibitor of ANT. This acid blocks NMDA receptor and prevents PARP cleavage and DEVDase(Caspase-2 like) activity so that it inhibits apoptosis of cerebrocortical neurons.

References

• “Signaling Events in NMDA Receptor-Induced Apoptosis in Cerebrocortical Cultures”

"An Inhibitor Of The Adenine Nucleotide Translocase Of Mitochondria”

Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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