C24H29N3O2 • HCl
FK-866 HCl is a highly specific, noncompetitive inhibitor of nicotinamide phosphoribosyltransferase inhibitor (Ki=0.4 nM). Induces tumor cell apoptosis via gradual intracellular depletion of NAD+. Extends lifespan of human cells mediated by activation of the longevity enzyme SIRT1. Suppresses colorectal cancer cell growth and sensitizes pancreatic adenocarcinoma cells to death by other agents. Cell permeable.
Research or further manufacturing use only, not for food or drug use.