DMF, DMSO, Ethanol
Necrostatin-1 inhibits necroptosis, a non-apoptotic cell death pathway. Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. Inhibits RIP1 kinase, the key upstream kinase involved in the activation of necroptosis (EC = 180 nM).
Research or further manufacturing use only, not for food or drug use.