Indian Saffron; Turmeric yellow
Curcumin is a cell-permeable, antioxidant that acts as a dual inhibitor of 5-lipoxygenase (IC= 8 M) and cyclooxygenase (IC= 52 M).
Curcumin also inhibits glutathione S-transferase,induction of nitric oxide in activated macrophages and inhibits EGF-induced tyrosine phosphorylation of EGF receptors. Also shown to be a p300/CREB-binding protein-specific inhibitor of histone acetyltransferase, inhibiting the acetylation of histones H3 and H4 with an ICof ~25 M. Does not affect p300/CREB binding protein-associated factor (PCAF).
Research or further manufacturing use only, not for food or drug use.