TAK-165
366017-09-6
468.5
C25H23F3N4O2
DMF, DMSO
-20°C
Mubritinib is a cell-permeable, potent inhibitor of the human epidermal growth factor receptor 2 (HER2) tyrosine kinase (IC= 6 nM). Displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. TAK 165 inhibits bladder, kidney and androgen-independent prostate cancer in vitro and in vivo.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.