Tyrphostin AG-1296
146535-11-7
266.3
C16H14N2O2
DMF, DMSO
-20°C
AG 1296 is a potent and selective inhibitor of PDGF receptor kinase, it inhibits ligand-stimulated DNA synthesis in platelet-derived growth factor receptor and stem cell factor receptor transfected cells. Treatment of sis oncogene transfected NIH3T3 cells with AG-1296 reverses the transformed phenotype.It also induces apoptosis in a small-cell lung cancer cell line (H526).
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
