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MK-2206 Hydrochloride, 1 MG

Price$ 60.75
  • SKU: M-2382-1MG
  • Pack Size: 1 MG
MK-2206 Hydrochloride, 1 MG



C25H21N5O • 2HCl



MK-2206 HCl is a highly selective non-ATP competitive allosteric Akt inhibitor with IC50s of 8 nM, 2 nM and 65 nM for Akt1, Akt2 and Akt3, respectively. MK-2206 potently inhibits phosphorylation of Thr and Ser in 3T3-L1 adipocytes with IC50 values of 0.11 and 0.18 µM, respectively as well as downstream effects of insulin on GLUT4 translocation (IC50 = 0.47 µM) and glucose transport (IC50 = 0.14 µM). In addition, treatment with MK-2206 causes a robust, concentration-dependent activation of autophagy in human glioma cell lines LN229 and T98G.


0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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