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LY294002 Solution (in DMSO), 5 MG

Price$ 108.00
  • SKU: E-2312-5MG
  • Pack Size: 5 MG
LY294002 Solution (in DMSO), 5 MG





LY294002 solution is a 10 mM (5 mg/1627 µl) solution of PI -3 Kinase inhibitor.

LY294002 is a cell-permeable, potent and specific phosphatidylinositol 3-kinase (PI 3-kinase) inhibitor that acts on the ATP-binding site of the enzyme (IC50 = 1.4 µM). Also inhibits nonhomologous DNA end-joining (NHED) in the 460 kDa phosphatidylinositol 3-like kinase DNA-PKcs, which is the catalytic subunit of DNA-activated protein kinase.

LY-294002 does not affect the activity of EGF receptor kinase, MAP kinase, PKC, PI 4-kinase, S6 kinase, and c-src at 50 µM. Blocks the proliferation of cultured rabbit aortic smooth muscle cells without inducing apoptosis. Reported to inhibit histamine secretion in RBL-2H3 cells (IC50 = 5 µM).


0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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