DMSO (50 mM)
A cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110), and mTOR. The ICvalues are 2, 8, 20, 26, 48, 83, 88, 150 nM for DNA-PK, p110, mTORC1, PI3-KC2, p110, mTORC2, p110, and p110, respectively. Inhibits growth of human tumor xenografts in mice in vivo.
Research or further manufacturing use only, not for food or drug use.