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Bisindolylmaleimide IX methanesulfonate, 5 MG

Price$ 367.25
  • SKU: R-2418-5MG
  • Pack Size: 5 MG

2-{1-[3-(Amidinothio)propyl]-1H-indol-3-yl}-3-(1-methylindol-3-yl)maleimide methanesulfonate




DMSO, Water


Bisindolylmaleimide IX methanesulfonate is a cell-permeable and potent inhibitor of protein kinase C (PKC) isoforms (IC50= 5, 24, 14, 27, and 24 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε, respectively).

It inhibits protein kinase A (PKA) (IC50 = 0.9 μM) and calcium/calmodulin kinase II (IC50 = 17 μM) at much higher concentrations. Also inhibits glycogen synthase kinase-3 (GSK-3) (IC50 = 6.8 nM).


0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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