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Price$ 225.00
  • SKU: U-2575-1MG
  • Pack Size: 1 MG

NSC 638850; ​7-hydroxy Staurosporine




DMSO, Ethanol


UCN-01 is an indolocarbazole isolated from a high staurosporine-producing Streptomyces culture. UCN-01 inhibits protein kinase C (PKC) and cyclin-dependant kinase 2 (CDK2), resulting in accumulation of cells in the G1 phase and induction of apoptosis. UCN-01 also enhances the cytotoxicity of other anti-cancer drugs, such as DNA-damaging agents and anti-metabolite drugs, through putative abrogation of G2 and/or S phase accumulation induced by the latter agents.


0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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