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Price$ 266.93
  • SKU: Y-1006-1ML
  • Pack Size: 1 ML





Y-27632 [(+)-(R)-trans-4-(1-aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride] is widely used as a specific inhibitor of the Rho-associated coiled-coil forming protein serine/threonine kinase (ROCK) family of protein kinases. Y-27632 inhibited the kinase activity of both ROCK-I and ROCK-II in vitro, and this inhibition was reversed by ATP in a competitive manner.

A specific Rho-associated kinase inhibitor, Y-27632, has been reported to inhibit cancer invasion. Y-27632 could be a promising therapeutic method when combined with chemotherapy for treating human neoplastic meningitis.

A 10 mM (3.20 mg in 1 ml) solution of the ROCK inhibitor Y-27632, Dihydrochloride (Cat. No 1596) in deionized water.

0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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