870483-87-7
366.41
C20H22N4O3
Soluble in DMSO (40 mg/ml)
-20°C
A small-molecule, ATP-competitive inhibitor of cFMS kinase; at 60 nM it inhibits human cFMS kinase completely in vitro and was inactive against 26 other kinases. GW2580 also inhibits lipopolysaccharide (LPS)-induced TNF production in mice, but not LPS-induced TNF production in freshly isolated human monocytes and mouse macrophages in vitro.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
