Veliparib
912445-05-7
317.2
C13H16N4O • 2HCl
DMSO, PBS (pH 7.2)
-20°C
ABT-888 HCl is a potent inhibitor of PARP-1 and PARP-2 (potency 5 nM in vitro). Does not inhibit other NAD-binding enzymes. Has minimal CYP450 inhibition and induction. Shows broad spectrum of chemo- and radio-potentiation. Does not show inherent cytotoxicity and shows no single agent activity in tumor models.
0.1 lbs
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