Cantharidine; Cantharone
56-25-7
196.2
C10H12O4
DMSO, Ethanol
-20°C
FOR RESEARCH USE ONLY. This product is strictly intended for legitimate research purposes. We reserve the right to refuse or cancel any orders that do not meet our compliance standards or are suspected of being intended for unauthorized or illegal use. By placing an order, you confirm that your use complies with all applicable laws and regulations.
Cantharidin is a terpenoid compound produced by blister beetles. It acts as a potent and selective inhibitor of protein phosphatase 2A (PP2A) and inhibits protein phosphatase 1 (PP1) at higher concentrations. Useful in inhibition of PP2A and PP1 during purification of phosphorylated proteins. This inhibitor also weakly suppresses the activity of protein phosphatase 2B (PP2B).
It is known that cantharidin induces apoptosis in many types of tumor cell. It is reported that it causes down-regulation of CCAT1 related to PI3K/Akt signaling so that inhibits proliferation and metastasis. The toxin is a poisonous vesicant and toxic to some pests.
Applications:
- Inhibitor of protein phosphatase 2A
- Used for anticancer agent
- Component of pesticides
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
