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Elastatinal, 5 MG

Price$ 84.45
  • SKU: E-2044-5MG
  • Pack Size: 5 MG
Quantity
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51798-45-9

512.56 Da

C21H36N8O7

Soluble in water up to 20 mg/mL. It has been reported to also be soluble in methanol, pyridine, and dimethyl sulfoxide, and slightly soluble in ethanol.  Alkaline solutions are unstable.

-20°C


Description

Elastatinal is a tetrapeptide derivative with an aldehyde group which is essential for inhibitory activity such as pancreatic elastase. It is a much stronger inhibitor of elastase from pancreas than from leucocytes because it’s isolated from Actinomycetes.

Elastatinal is a highly specific inhibitor of elastase-like serine proteases. Elastatinal can also be used as an inhibitor for thermitase, a thermostable serine protease from Thermoactinomyces vulgaris, and for macroglobulin-protease complexes.

Elastatinal inhibits the proteolytic activity of poliovirus and rhinovirus 2A proteinases in vitro. Additionally, it has no effect on DNA repair and UV-induced sister chromatid exchanges, and inhibits the cleavages found at Ala-Ala bonds in peptides that represent the capsid/nucleocapsid site. Elastatinal is an irreversible inhibitor of neutrophil and rat microglia elastase.

Applications:

• Used as a microbial product inhibitor for elastase
• Ability to reduce rate of degradation of endostain
• Used to effectively inhibit phenylmethylsulfonyl fluoride
Ability to inhibit poliovirus and rhinovirus 2A proteinases in vitro

Specifications

• EC Number: 257-426-7

Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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