DMSO (~ 10 mg/ml)
Cell-permeable. A potent, selective, non-transition state and non-competitive inhibitor of γ-secretase (IC= 0.3 nM for totalamyloid) and Notch processing. At higher concentrations (20-400 M), only weakly affects the presenilase activity.
Research or further manufacturing use only, not for food or drug use.