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Price$ 219.50
  • SKU: S-2434-10MG
  • Pack Size: 10 MG
Quantity
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2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide

304896-28-4

434.3

C23H13Cl2N3O2

DMF, DMSO

-20°C


AGK2 is a potent inhibitor of sirtuin 2 (SIRT2) (IC= 3.5 M). AGK2 is 15-fold more selective for SIRT2 than SIRT1 and SIRt3. Inhibition of SIRT2 rescued synuclein toxicity and modified inclusion morphology in a cellular model of Parkinsons disease.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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