TCEP Hydrochloride

SKU
T-1180
  • CAS:51805-45-9
  • Formula:C9H15O6P • HCl
  • MW:286.6 Da
  • Appearance:White crystalline solid
  • Purity:≥98.0%

0

3

0

Hazardous

Starting at $39.99

Product Name Qty
TCEP Hydrochloride
5 g
$184.99
TCEP Hydrochloride
10 g
$349.99
TCEP Hydrochloride
1 g
$39.99

Description

TCEP hydrochloride is a non-thiol reducing agent used to reduce and break disulfide bonds. TCEP HCl is widely preferred to the similar reducing agent DTT because of its greater effectiveness and resistance to oxidation from air exposure.

Applications

TCEP HCl finds wide use in biochemical research due to its ability to reduce disulfide bonds in proteins and peptides. Along with DTT, TCEP HCl is frequently used as a main reducing agent in studies of proteins and their properties. Under some circumstances, TCEP HCl can even be employed for a simultaneous process of reduction and digestion of proteins featuring disulfide bonds. The advantage of this process is the increase in sequence coverage it is capable of producing.

Specifications

• Ordoless disulfide reducing agent.
• More stable, resistant to air oxidation and effective than DTT
• pH range is 1.5 to 8.5

 

More Information
Alternate Name/Synonyms
Tris(2-carboxyethyl)phosphine hydrochloride; TCEP; TCEP HCl
SKU
T-1180
CAS #
51805-45-9
Chemical Name
3-[bis(2-carboxyethyl)phosphanyl]propanoic acid;hydrochloride
Chemical Formula
C9H15O6P • HCl
Molecular Weight
286.6 Da
Appearance
White crystalline solid
Purity
≥98.0%
Solubility
Soluble in water
Melting Point
179-180 °C
Preparation
N/A
Storage Temp
-20°C, desiccated
THERAPEUTIC AREA
Not Applicable
USE
TCEP Hydrochloride is used for selective reduction of disulfides and is more stable than DTT. It is useful in mass spectrometry applications.
Merck Index
N/A
MDL NUMBER
MFCD00145469
CHEMACX
X1074093-3
INCHI
InChI=1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H
SMILES
C(CP(CCC(=O)O)CCC(=O)O)C(=O)O.Cl
GHS Pictograms
8
UN #'S
UN 3261
PACKING GROUP
II
Handling
Always wear personal protective equipment.
msds 1
/media/upload/pdf/T-1180, TCEP . HCL, SDS, diamond format.pdf
Certificate of Analysis 1
/media/upload/pdf/T-1180, J1052B.pdf
Certificate of Analysis 2
/media/upload/pdf/T-1180, J1052A.pdf
Certificate of Analysis 3
/media/upload/pdf/T-1180, J1052.pdf
Spec
GHS PICTOGRAMS
Handling Always wear personal protective equipment.
UN #'S UN 3261
Packing Group II
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