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Vancomycin HCl, 1 G

Price$ 405.00
  • SKU: V-1065-1GM
  • Pack Size: 1 G
Quantity
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Vancomycin hydrochloride; Lyphocin; Vancor ; Vancocin

1404-93-9

1485.7

C66H75Cl2N9O24 • HCl

Water

2-8°C


Vancomycin HCl is a glycopeptide antibiotic that inhibits the growth of gram-positive microorganisms, such as MRSA (methicillin-resistant Staphylococcus aureus). It is isolated from Streptomyces orientalis and was first discovered within a soil sample found in Borneo in 1953.

Vancomycin hydrochloride interferes with microbial cell wall synthesis by inhibiting the incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. Vancomycin is often used with cefotaxime or carbenicillin to produce a wide spectrum of activity against both Gram-positive and Gram-negative bacteria.

Vancomycin HCl is commonly used in concentrations in the range of 50-100 μg/ml. Potency: >1,000 μg per mg.


Applications:

  • Treatment of severe infections caused by strains of methicillin-resistant (β-lactam-resistant) staphylococci.
  • Blocks bacterial cell wall synthesis
  • Studies involving cancer patients
  • Studies on antibiotic resistance
  • Nanoparticle transport studies

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.
  • Appearance: White, almost white or tan to brown.
  • Identification A (IR): Conforms to reference
  • Identification B (Chloride): Meets the requirements
  • Solubility: Freely soluble in water, Insoluble in ether and chloroform
  • pH (50mg/ml H2O): 2.5 - 4.5
  • Water: ≤ 5.0 %
  • Residue on Ignition: ≤ 1.0 %
  • Assay (anhydrous basis): ≥ 900  µg/mg
  • Vancomycin B: ≥ 90.0 %
  • Related Substance-A (N-demethyl Vancomycin B): ≤ 4.0 %
  • Related Substance-B (Desamido Vancomycin B): ≤ 4.0 %
  • Related Substance-C (Agluco Vancomycin B): ≤ 4.0 %
  • Related Substance-D (Desvancosaminyl Vancomycin B): ≤ 4.0 %
  • Related Substances (Any other individual impurity): ≤ 5.0 %
  • Related Substances (Total Impurities): ≤ 10.0 %
  • Monodechlotovancomycin: ≤ 4.7 %
  • Bacterial Endotoxins: ≤ 0.33 EU/mg
  • Total Aerobic Microbial Count: ≤ 100 CFU/g
  • Total Combined Yeast and Mold Count: ≤ 10 cfu/g
  • Grade: USP
  • Non Animal Origin: Non Animal Origin
  • Country of Origin: Reported as

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