
Description
A fungal metabolite that specifically inhibits phosphatidylinositol 3-kinase (PI-3), mitogen-activated protein kinase(MAPK) and myosin light-chain kinase (MLCK).Glycogen Synthase Kinase-3 Plays a Central Role in Mediating Glucocorticoid-Induced Apoptosis, Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells.Nongenotropic, Anti-Apoptotic Signaling of 1,25(OH)2-Vitamin D3 and Analogs through the Ligand Binding Domain of the Vitamin D Receptor in Osteoblasts and Osteocytes: MEDIATION BY Src, PHOSPHATIDYLINOSITOL 3-, AND JNK KINASES
Applications
• exhibits broad spectrum antifungal activity
• antitumor and antiinflammatory activity
• cell biology reagent in research to inhibit DNA repair
Additional Reading: Popular Anti-Fungal Drugs
GHS PICTOGRAMS | ![]() |
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Handling | WARNING! Very TOXIC PROTECT FROM LIGHT & MOISTURE! Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust. |
UN #'S | UN 3462 |
Packing Group | I |