Ampicillin Sodium Salt
- Formula:C16H18N3O4S • Na
- MW:371.4 Da
- Appearance:White powder
Ampicillin is a β-lactam antibiotic within the penicillin family. As a member of this family, Ampicillin is susceptible to β-lactamase, which hydrolyzes the β-lactam ring. This broad spectrum antibiotic is effective against gram-positive, gram-negative bacteria and anaerobic bacteria.
Ampicillin is widely used in cell culture as a selective agent it is also used for selection of ampicillin resistant bacteria. As an antibiotic, Ampicillin binds to penicillin-binding proteins (PBPs) on a susceptible organism and inhibits cell wall synthesis by interfering with the enzymes responsible for the formation of the organisms cell wall. After binding to the PBPs, Ampicillin acts as a structural analog of acyl-D-alanyl-D-alanine, acylates the transpeptidase enzyme and thereby prevents the cross-linking of the peptidoglycan of the cell wall necessary for the growth of the bacterium.
|Handling||Hygroscopic! Protect from moisture! Harmful irritant! Avoid contact with skin, eyes or clothing. Wash contaminated clothing before reuse. Do not eat, drink or smoke when using this product. Use personal protective equipment as required. Do not breathe dust/fume/gas/mist/vapors/spray. Use with local exhaust ventilation. Corrosive hazard. Wear protective gloves/clothing and eye/face protection|