DTE (1,4-Dithioerythritol)

SKU
D-2589
  • CAS:6892-68-8
  • Formula:C4H10O2S2
  • MW:154.25 Da
  • Appearance:White crystals
  • Purity:≥99%

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Starting at $39.99

Product Name Qty
DTE [Dithioerythreitol]
5 g
$64.99
DTE [Dithioerythreitol]
1 g
$39.99
DTE [Dithioerythreitol]
25 g
$224.99
DTE [Dithioerythreitol]
10 g
$99.99
DTE [Dithioerythreitol]
100 g
$749.99

Description

1,4-Dithioerythritol, typically abbreviated as DTE, is a sulfur-containing sugar that is derived from erythrose. DTE is one of two Cleland's reagents, while the other one, DTT, is an epimer of DTE. DTE can act as a protective agent for thiol groups. DTE acts as a reducing agent for disulfide bonds and is used to maintain -SH groups in the reduced state.

Applications

Both DTE and DTT are used widely in biochemical research applications. Specifically, DTE often used to reduce disulfide bonds to sulfhydryl groups, which it is then capable of protecting from oxidation. In this capacity, DTE has been used in studies researching topics from apoptosis to the use of mass spectroscopy to study nucleic acids. DTE's ability to prevent oxidation of sulfhydryl groups also makes it useful for SDS polyacrylamide gel electrophoresis.

More Information
Alternate Name/Synonyms
Dithioerythritol; Cleland's Reagent
SKU
D-2589
CAS #
6892-68-8
Chemical Name
(2R,3S)-1,4-bis(sulfanyl)butane-2,3-diol
Chemical Formula
C4H10O2S2
Molecular Weight
154.25 Da
Appearance
White crystals
Purity
≥99%
Solubility
Soluble in water and methanol
Melting Point
> 81⁰C
Storage Temp
+4°C, desiccated, under nitrogen
THERAPEUTIC AREA
Not Applicable
USE
Dithioerythritol is an epimer of dithiothreitol and an erythro isomer of 2,3-dihydroxy-1,4- dithiolbutane. The compound is a protective agent for thiol groups and strong reducing agent that is capable of reducing disulfide bonds.
Handling
Further processing of solid materials may result in the formation of combustible dusts. The potential for combustible dust formation should be taken into consideration before additional processing occurs. Provide appropriate exhaust ventilation at places where dust is formed.
Certificate of Analysis 1
GHS PICTOGRAMS
Handling Further processing of solid materials may result in the formation of combustible dusts. The potential for combustible dust formation should be taken into consideration before additional processing occurs. Provide appropriate exhaust ventilation at places where dust is formed.
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