MES, Anhydrous, Ultrapure

SKU
M-2699
  • CAS:4432-31-9
  • Formula:C6H13NO4S
  • MW:195.24 Da
  • Appearance:White powder
  • Purity:≥99.0%

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Product Name Qty
MES, Anhydrous, Ultrapure
100 g
$49.99
MES, Anhydrous, Ultrapure
1 kg
$375.00
MES, Anhydrous, Ultrapure
500 g
$214.99
MES, Anhydrous, Ultrapure
250 g
$119.99

Description & Applications

2(N-Morpholino)ethanesulfonic acid, typically abbreviated as MES, is an ultrapure zwitterionic buffer classed as one of Good's buffers. It is used widely as a buffer in assays for biochemical studies. In this capacity, MES has been applied in research relating to enzymes, receptor interactions, cytoskeletal structures and several other areas of biochemistry. MES is particularly preferred for the characterization of smaller proteins.

This buffer can also be used to maintain appropriate pH balance in plant cell cultures without impairing regular growth. One study analyzing the effects of MES on nodulation in flowering plants of the genus Medicago found that concentrations of the buffer of 2 mM and above increased nodulation rates, while concentrations as high as 10 mM exerted no observable inhibitory effect on growth. MES is not absorbed across cell membranes.

Specifications

• EC Number: 224-632-3
• pH Range: 6-8
• pKa @ 25ºC: 6.10

 

More Information
Alternate Name/Synonyms
2-(N-Morpholino)ethanesulfonic acid, 4-Morpholineethanesulfonic acid, Good's buffer
SKU
M-2699
CAS #
4432-31-9
Chemical Name
2-morpholin-4-ylethanesulfonic acid
Chemical Formula
C6H13NO4S
Molecular Weight
195.24 Da
Appearance
White powder
Purity
≥99.0%
Solubility
Soluble in water.
Melting Point
300°C
Storage Temp
Room temperature
THERAPEUTIC AREA
Not Available
USE
MES, Anhydrous, Ultrapure has been used in the MS (Murashige and Skoog) media for growth of Arabidopsis seedlings and has been added in the cytoskeleton buffer during immunofluorescence study. It is also used as a running buffer for resolving very small proteins on bis-tris gels and in cation-exchange chromatography.
Merck Index
14: 5902
MDL NUMBER
MFCD00149409
CHEMACX
X1009953-3
PubChecm ID
78165
INCHI
SXGZJKUKBWWHRA-UHFFFAOYSA-N
SMILES
C1COCCN1CCS(=O)(=O)O
RTECS
QE3479500
Handling
Wear personal protective equipment. Ensure adequate ventilation. Avoid contact with skin, eyes and clothing. Avoid ingestion and inhalation. Avoid dust formation.
GHS PICTOGRAMS
Handling Wear personal protective equipment. Ensure adequate ventilation. Avoid contact with skin, eyes and clothing. Avoid ingestion and inhalation. Avoid dust formation.
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