Glumamycin; Amfomycin; A1437E
1402-82-0
1290.4
C58H91N13O20
DMSO, DMF, Ethanol
-20°C
Amphomycin is a lipopeptide antibiotic produced by Streptomycetes and Actinoplanes, initially reported by researchers at Bristol-Myers in 1953 from Streptomyces canus. Amphomycin was marketed as a complex of closely related analogues in the 1950s and 1960s. Structure elucidation was not completed until 2000.
Amphomycin is active against Gram-positive bacteria, inhibiting peptidoglycan synthesis and blocking cell wall development. It is closely related to a number of “lost” antibiotics, aspartocin, crystallomycin, glumamycin, friulimicin, laspartocin, tsushimycin and zaomycin.
Interest in amphomycin was re-awakened with the discovery of friulimicin activity against antibiotic resistant strains.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
