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Aphidicolin, 5 MG

Price$ 476.50
  • SKU: A-1026-5MG
  • Pack Size: 5 MG
Quantity
-
+

APC; ICI 69653; NSC 234714

38966-21-1

338.5

C20H34O4

DMSO, Methanol

-20°C


Aphidicolin is a reversible inhibitor of nuclear DNA replication in eukaryotes and some animal viruses. It interferes with dCTP-specific binding sites on DNA polymerase-α. It also works on other DNA polymerases, however it does not work on DNA polymerase-β. 
 

Viruses inducing DNA polymerase-α, such as Herpes simplex, can be affected by aphidicolin because of its mechanism. It could be used for clinical study.
 

Isolated from Nigrospora oryzae.


Applications:

  • Control of cell proliferation
  • DNA pol-β studies
 
 ​​​​

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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