Erythromycin cyclocarbonate
55224-05-0
759.9
C38H65NO14
DMF, DMSO, Ethanol
-20°C
Davercin (erythromycin A cyclic 11,12-carbonate) is a first generation semi-synthetic erythromycin. Davercin is prepared by coupling the 11- and 12-OH groups to form a cyclic carbonate.
This simple modification improves the stability and hydrophobicity of the macrocyclic structure. Davercin shows comparable or better in vitro potency, low host toxicity and improved pharmacokinetics compared with erythromycin.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
