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Dirithromycin, 1 G

Price$ 193.50
  • SKU: D-2525-1GM
  • Pack Size: 1 G
Quantity
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Antibiotic AS-E 136; LY237216

62013-04-1

835.1

C42H78N2O14

DMF, DMSO, Ethanol

-20°C


Dirithromycin is a macrolide antibiotic pro-drug of 9S-erythromycylamine, a close analogue of erythromycin in which the 9-keto group is replaced with an amino group in the S-configuration. Although erythromycylamine overcomes the acid instability of erythromycin, it is poorly absorbed following oral administration.

Dirithromycin is formed by reacting erythromycylamine with an aldehyde to form a Schiff base which undergoes cyclisation to an oxazine with the C11-alcohol. Dirithromycin provides higher tissue levels and prolonged in vivo half-life by slowly releasing erythromycylamine.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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