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Apicidin, 1 MG

Price$ 64.76
  • SKU: A-1264-1MG
  • Pack Size: 1 MG




Soluble in ETOH, DMSO (1mg/mL)



Apicidin is a novel fungal metabolite that is a potent chemotherapeutic and anti-protozoal agent, exhibiting anti-histone deacetylase activity.

It inhibits cell proliferation and antitumor effects in several human cancer cell lines by inducing apoptosis via Fas/Fas ligand. The metabolite arrests the cell cycle at the G1 phase and induces p21 and gelsolin, therefore, it has shown a potential antiproliferative property.

It is used for treatment of parasites in vitro due to its target, histone deacetylase. The acetylation and deacetylation of histones are considered essential in gene expression and it has been proven that histone deacetylation inhibitors have antiparasitic effects.



• Chemotherapeutic agent

• Antiprotozoal agent

• Used as an inhibitor of histone deacetylation



• “Apicidin: A novel antiprotozoal agent that inhibits parasite histone deacetylase”

• “Apicidin, a Histone Deacetylase Inhibitor, Inhibits Proliferation of Tumor Cells via Induction of p21WAF1/Cip1 and Gelsolin”

• “Apicidin, a Histone Deacetylase Inhibitor, Induces Apoptosis and Fas/Fas Ligand Expression in Human Acute Promyelocytic Leukemia Cells”

• “Apicidin is a histone deacetylase inhibitor with anti-invasive and anti-angiogenic potentials”


Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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