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Capecitabine, 1 G

Price$ 120.25
  • SKU: C-2217-1GM
  • Pack Size: 1 G
Quantity
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+

Ro 09-1978; 5'-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]-cytidine

154361-50-9

359.4

C15H22FN3O6

DMF, DMSO, Ethanol

-20°C


Capecitabine is a pre-prodrug of 5-fluorouracil (5-FU).  After oral uptake, capecitabine is first metabolized to 5'-deoxy-5-fluorocytidine (5'-DFCR), which occurs mainly in the liver by carboxyl-esterase.  The metabolite is converted to 5'-deoxy-5-fluoro-uridine (5'-DFUR) by cytidine deaminase in liver and tumor tissue.  Then 5'-DFUR is converted to 5-FU intracellularly by thymidine phosphorylase, which is often expressed in tumor tissue.
 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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