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Ionomycin, Free Acid, 1 MG

Price$ 96.48
  • SKU: I-1014-1MG
  • Pack Size: 1 MG
Quantity
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Frequently Bought Together

Total price: $ 2,688.43

This item: Ionomycin, Free Acid, 1 MG $ 96.48

CHAPS, High Purity, 1 KG $ 2,591.95

56092-81-0

709

C41H72O9

DMSO/DCM/CH3OH: clear colorless solution at 10 mg/ml

+4°C


Description

Ionomycin is a highly specific ionophore isolated from Streptomyces conglobatus. It acts as a transport carrier of divalent cations, helping the cations across solvent barriers. It is used to study calcium transport across the plasma membrane.

It is known to induce apoptosis in some cell lines. For example, it is reported that ionomycin promotes apoptosis in immature B cells and regulates cell cycle in mature B cells. It is also believed that the ionophore induces apoptotic degeneration of embryonic cortical neurons.

Ionomycin is also used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2 and IL-4 usually in conjunction with PMA.

 

Applications

• Ca2+ ionophore

• Antibiotic

 

References

• “Regulation of cell division of mature B cells by ionomycin and phorbol ester.”

• “Characterization of ionomycin as a calcium ionophore.”

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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