The solubility of DDTT in mixtures of anhydrous pyridine and acetonitrile or anhydrous pyridine and THF is relatively limited and increases with the increasing concentration of pyridine.
DDTT, popularly known as Beaucage Reagent, has found common use for the sulfurization of oligonucleotides because of its high efficiency, fast reaction time, and widespread availability.
Solubility of DDTT
|Concentration of DDTT||Pyridine:ACN||Pyridine:THF|
Research or further manufacturing use only, not for food or drug use.