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Temsirolimus, 5 MG

Price$ 319.61
  • SKU: T-2453-5MG
  • Pack Size: 5 MG
Quantity
-
+

162635-04-3

1030.29

C56H87NO16

Soluble in chloroform, methanol, DMSO (75 mg/ml at 25 °C), water (1 mg/ml at 25 °C), and ethanol (75 mg/ml at 25 °C)

-20°C


mTOR inhibitor with anti-cancer activity. Temsirolimus is a semisynthetic macrocyclic lactone prepared from rapamycin by selective acylation of the 42-hydroxy group with a protected bis(dihydromethyl)propionic acid, followed by deprotection. It has anti-angiogenic effects which may contribute to the antitumor activity of temsirolimus observed in breast cancer. Temsirolimus shows synergistic in vivo anti-myeloma effects in combination with dexamethasone in a xenograft model. Temsirolimus is extensively cited in the literature with over 700 citations.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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