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Bafilomycin A1, 1 MG

Price$ 226.80
  • SKU: B-1183-1MG
  • Pack Size: 1 MG
Quantity
-
+

88899-55-2

622.8

C35H58O9

Soluble in ethanol, methanol, DMF or DMSO. DMSO @ 50mg/ml. Poor water solubility.

-20°C


A macrolide antibiotic that acts as a specific inhibitor of vacuolar-type H+-ATPase. Useful in distinguishing among different types of ATPases. Endothelin-converting enzyme 1 degrades neuropeptides in endosomes to control receptor recycling. Post-endocytic sorting of calcitonin Receptor-like Receptor and Receptor Activity-Modifying Protein 1. Additionally, Bafilomycin A1 prevents lysosomal cholesterol trafficking in macrophages and can be used to distinguish different types of ATPases. Research shows that Bafilomycin A1 can inhibit macroautophagy and promote apoptosis in colon cancer cells.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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