Soluble in 100% ethanol and DMSO.
Monastrol is a potent, cell permeable non-tubulin-interacting mitosis inhibitor. Monastrolblocks mitosis (IC= 14 M) by binding to the mitotic kinesin Eg5, a motor protein required for spindle bipolarity.Seeking published researchers utilizing our Monastrol product? Hit the link for the full paper.MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochore attachment.Functional Analysis of Human Microtubule-based Motor Proteins, the Kinesins and Dyneins, in Mitosis/Cytokinesis Using RNA Interference.
Research or further manufacturing use only, not for food or drug use.