4311-88-0
259.332
C13H13N3OS
Soluble in DMSO (25mg/ml) or EtOH(6mg/ml)
-20°C
Inhibits necroptosis, a non-apoptotic cell death pathway. Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. Inhibits RIP1 kinase, the key upstream kinase involved in the activation of necroptosis (EC = 180 nM)
0.1 lbs
Research or further manufacturing use only, not for food or drug use.