4311-88-0
259.332
C13H13N3OS
Soluble in DMSO (25mg/ml) or EtOH(6mg/ml)
-20°C
Inhibits necroptosis, a non-apoptotic cell death pathway. Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. Inhibits RIP1 kinase, the key upstream kinase involved in the activation of necroptosis (EC = 180 nM)
0.1 lbs
CAS Number:29925-17-5
CAS Number:71-62-5
Molecular Formula:C36H51NO11
Substance Name:6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)pyridin-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one; PD-332991
CAS Number:571190-30-2
Molecular Formula:C24H29N7O2
Substance Name:5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidino-1H-pyrazole-3-carboxamide; SR141716
CAS Number:168273-06-1
Substance Name:N-[(2R)-2-(Hydroxamidocarbonylmethyl)-4-methylpentanoyl]-L-tryptophan methylamide; GM-6001
CAS Number:142880-36-2
Molecular Formula:C20H28N4O4
Substance Name:Suberoylanilide hydroxamic acid; Vorinostat; MK-0683; N-Hydroxy-N'-phenyloctanediamide
CAS Number:149647-78-9
Substance Name:2-Cyano-N-(2,5-dibromophenyl)-3-hyd¬roxy-2-butenamide
CAS Number:62004-35-7
Molecular Formula:C11H8Br2N2O2
CAS Number:944261-79-4
Substance Name:6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)pyridin-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one; PD-332991
CAS Number:571190-30-2
Molecular Formula:C24H29N7O2
CAS Number:29925-17-5