CID-1088438; ML-130
799264-47-4
287.3
C14H13N3O2S
DMF, DMSO
-20°C
Nodinitib-1 is a cell-permeable, selective NOD1 (nucleotide-binding oligomerization domain 1) inhibitor. Selectively inhibits NOD1-dependent activation of NF-kB in HEK293 cells (IC= 0.560.04 M). Displays high selectivity (36-fold) over MDP-stimulated signaling in reporter cell lines containing both endogenous and overexpressed NOD2 proteins or TNF-induced NF-kB activation.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.