66701-25-5
357.4
C15H27N5O5
Up to 20mg/ml in water, Up to 25mg/ml in DMSO
-20°C
Description
E-64 is an Irreversible, potent and highly selective inhibitor of cysteine proteases. It does not affect cysteine residues in other enzymes. E64 acts by forming a thioether bond with the thiol of the active cysteine. E-64 will not inhibit serine proteases (except trypsin) but inhibits activation-induced programmed cell death and restores defective immune responses in HIV. Specific active site titrant.
Applications
• Used as an inhibitor for calpain, papain, and cathepsin B, cathepsin L
• Used to study excystation in Giardia lamblia
• Used to reduce inflammation in cystic fibrosis patients
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
