LBH-589
404950-80-7
349.43
C21H23N3O2
DMSO
-20°C
Panobinostat is a highly potent inhibitor of both histone deacetylase 1 (HDAC1) activity and tumor cell proliferation in vitro.
The IC50 values of HDAC isozymes HDAC1-IP Ac-H4, HDAC8, MALunselective, B61HDAC1 and B12HDAC6 are 0.230.06, 28329, 754, 475 and 8912 nM, respectively. And to A2780 proliferation, IC50 value is 4.61.8 nM.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.