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Price$ 83.75
  • SKU: A-2189-5MG
  • Pack Size: 5 MG

​ATM Kinase Inhibitor




DMF, DMSO, Ethanol


Ku-55933 is a potent, selective and ATP-competitive inhibitor of ATM Kinase (K = 2.2 nM; IC= 13 nM). Inhibits DNA-PK, mTOR, PI 3-K, PI 4-K, and ATR at much higher concentrations (IC= 2500, 9300, 16600, 100000 and 100000 nM, respectively). KU-55933 inhibits cancer cell proliferation by inducing G(1) cell-cycle arrest. Sensitizes cells to ionizing radiations and chemotherapeutics. Induces apoptosis in breast and prostate cancer cell lines. 


0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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