937174-76-0
425.5
C21H27N7O3
DMF, DMSO
-20°C
GSK690693 is an ATP-competitive pan-Akt kinase inhibitor. Inhibits Akt kinase isoforms 1, 2, 3 with IC₅₀ values of 2, 13, and 9 nM, respectively. Inhibited proliferation and induced apoptosis in a subset of tumor cells with potency consistent with intracellular inhibition of Akt kinase activity.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.