9-Bromopaullone; NSC 664704
142273-20-9
327.2
C16H11BrN2O
DMF, DMSO
-20°C
Paullones represent a novel class of small molecule cyclin-dependent kinase (CDK) inhibitors. Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC50=400 nM) also inhibits CDK2/cyclin A (IC50=680 nM). Weaker effect on other kinases. Also shown to inhibit GSK-3β (IC50=23 nM).
0.1 lbs
Substance Name:Changchuanmycin; FK-520; FR900520; Immunomycin; L 683590
CAS Number:104987-12-4
Substance Name:3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one; 2',7-Dihydroxy-3,4-benzocoumarin
CAS Number:1143-70-0
Substance Name:3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one; 2',7-Dihydroxy-3,4-benzocoumarin
CAS Number:1143-70-0
Substance Name:3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one; 2',7-Dihydroxy-3,4-benzocoumarin
CAS Number:1143-70-0
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CAS Number:114977-28-5
Substance Name:N-Debenzoyl-N-(t-butoxycarbonyl)-10-deacetyltaxol; Taxotere; RP-56976; NSC-628503
CAS Number:114977-28-5